The panzootic spread of highly pathogenic avian influenza H5N1 sublineage 2.3.4.4b: a critical appraisal of One Health preparedness and prevention
With the world gradually recovering from the COVID-19 pandemic, it is important to think forward when it comes to prevention of infectious disease outbreaks originating from the animal world.
Scientific Papers
News
Article
Omicron BA.2 breakthrough infection elicits CD8+ T cell responses recognizing the spike of later Omicron subvariants
Recent studies have suggested that memory T cells play a critical role in protecting individuals immunized with SARS-CoV-2 vaccines against variants
Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19 List of authors.
Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation
During the COVID-19 pandemic, levels of seasonal influenza virus circulation were unprecedentedly low, leading to concerns that a lack of exposure to influenza viruses, combined with waning antibody titres.
Inflammageing mediated by cytotoxic lymphocytes is associated with diabetes duration
Type 2 diabetes is associated with increased tumor necrosis factor-α by CD8 T cells. Increased granzyme B production by natural killer cells and γδ T cells is observed in type 2 diabetes.
How well does a flu vaccine work? DRIVE project evaluates performance
Despite challenging conditions posed by the COVID-19 outbreak, the DRIVE project successfully tested how well various brands of flu vaccines worked across five European countries and a range of age groups.
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Policy & Recommendations
Data-informed decision-making: Driving life-course immunisation in National Immunisations Programs (NIPs)
CLCI, together with MEP Tomislav Sokol and the European Institute for Innovation through Health Data, has produced a report exploring ways of improving the use of data in national immunisation programme planning.
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Article
Scientific Papers
Real-World Effectiveness of BNT162b2 Against Infection and Severe Diseases in Children and Adolescents
The efficacy of the BNT162b2 vaccine in pediatrics was assessed by randomised trials before the Omicron variant’s emergence.
Simvastatin in Critically Ill Patients with Covid-19
The efficacy of simvastatin in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear.
Public health action needed to mitigate the impact of respiratory pathogens for 2023-24 winter season in Europe
In an epidemiological update, the ECDC urges EU/EEA Member States to strengthen vaccination campaigns and prepare for the possible need to increase emergency department and ICU capacity
Evaluation of the effectiveness and impact of Nirsevimab in Galicia
The NIRSE-GAL study shows in real time the evolution of the coverage achieved by immunisation with Nirsevimab in children and compares RSV admissions in different population groups of children and adults in Galicia in Spain with previous years.
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Policy & Recommendations
Study on the coherence, complementarity, and continued relevance of actions in the Council Recommendation on strengthened cooperation against vaccine-preventable diseases
Since 2018, the work of the European Commission on vaccination has been guided by the Council Recommendation on strengthened cooperation against vaccine-preventable diseases. The aim of this report is to support possible policy developments in the future.