Adult obesity and risk of severe infections: a multicohort study with global burden estimates
Adult obesity has been linked to specific infections, but evidence across the full spectrum of infectious diseases remains scarce.
Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart
Abundant evidence has correlated influenza infection with cardiovascular disease, yet mechanisms linking infection with the heart remain poorly understood.
Influenza vaccination and the risk of myocardial infarction: a meta-epidemiology study
The association between influenza vaccination and the risk of myocardial infarction (MI) remains incompletely characterized, particularly in real-world populations.
Interim 2025/26 influenza vaccine effectiveness estimates with immuno-epidemiological considerations for A(H3N2) subclade K protection, Canada, January 2026
In a pre-season influenza risk assessment publicly posted in October 2025, Canadian investigators used global genomic and antigenic surveillance data to highlight important mutations in circulating influenza A(H3N2) viruses.
Antigenic Drift and Antivaccine Shift in the 2025–2026 Influenza Season
Both viral and host factors have contributed to the intensity of influenza activity during the 2025–2026 season. Some of these factors can be managed, whereas others are largely beyond human control.
Population effects of influenza vaccination in children and adolescents: Systematic review
To investigate indirect vaccine effectiveness (indirVE) of vaccination of children and adolescents with seasonal influenza vaccines against influenza-related outcomes occurring in other population groups.
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase
Human influenza A viruses escape antibody-mediated immunity through changes in the hemagglutinin (HA) and neuraminidase (NA) glycoproteins.
New analysis indicates that vaccines greatly reduce hospitalisations for flu and COVID-19
A new modelling study from RespiCompass, the ECDC Respiratory Diseases Scenario Modelling Hub, indicates that influenza and COVID-19 vaccination programmes markedly reduced hospitalisations among older adults across Europe in the 2024/25 season.
